University of Pennsylvania (Penn-CEIRR)
Philadelphia, PA | United States
Lead Organization: University of Pennsylvania
About Penn-CEIRR
The Penn-CEIRR brings together a collaborative group of scientists focusing on influenza virus surveillance, epidemiology, immunology, virology, evolutionary biology, clinical studies, and modeling. We have an extensive influenza virus surveillance program that includes sampling in the United States, Hong Kong, Cambodia, the United Kingdom, and Bangladesh. Our Center is completing studies to determine how immune responses to influenza viruses develop across different populations with high and low vaccination risks, and we are identifying immune responses associated with protection versus susceptibility. We are completing a series of human and animal studies to determine how prior influenza virus exposures shape immune responses to new viral strains, and we are developing models to forecast influenza virus evolution and epidemiology based on experimentally measured variations in immune specificities across different populations. We are studying pathogens with pandemic potential, including emerging swine and avian influenza virus strains. Combined, our efforts will fill critical knowledge gaps in influenza virus and other emerging pathogen research, reveal factors underlying viral emergence and transmission, and accelerate development of new and improved control measures.
Leadership

Institutions & Investigators
University of Pennsylvania
Michael Betts, PhD
Professor, Department of Microbiology
Sara Cherry, PhD
Professor, Department of Pathology and Laboratory Medicine
Scott Hensley, PhD
Professor, Department of Microbiology
John Wherry, PhD
Chair, Department of Systems Pharmacology and Translational Therapeutics
Institutions & Investigators
University of Pennsylvania
- Michael Betts, PhD, Professor, Department of Microbiology
- Sara Cherry, PhD, Professor, Department of Pathology and Laboratory Medicine
- John Wherry, PhD, Chair, Department of Systems Pharmacology and Translational Therapeutics
- Scott Hensley, PhD, Professor, Department of Microbiology
Animal and Plant Health Agency
Chattogram Veterinary and Animal Sciences University (CVASU)
Emory University
Fred Hutchinson Cancer Center
Institut Pasteur du Cambodge
Institute of Epidemiology, Disease Control and Research (IEDCR)
Iowa State University
Royal Veterinary College of London
Scripps Research Institute
Stanford University
United States Department of Agriculture
University of Arizona
University of Chicago
University of Hong Kong
University of Michigan
Center Coordinator
- Elizabeth Troisi, PhD, Center Coordinator, University of Pennsylvania